Mesothelioma and Non Asbestos Exposure Mesothelioma most commonly develops in the lung lining (pleura) and abdomen (peritoneum). The rare cancer may also develop in the linings around the heart or the testes (pericardium). Asbestos exposure is the primary risk factor for mesothelioma. Certain mesothelioma patients have no prior history of exposure to asbestos. Ex
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